Mucormycosis, a fungal infection in Covid-19 patients with uncontrolled diabetes and prolonged stays in intensive care, can be fatal if left untreated, the center said on Sunday.
An expert opinion also states that the fungal infection primarily affects people who take drugs that reduce their ability to fight environmental pathogens.
The evidence-based advice for screening, diagnosis and management of the disease was provided by the Indian Council for Medical Research (ICMR) and the Union Ministry of Health.
“Mucormycosis, if left untreated, can be fatal. The sinuses or lungs of such people are affected after fungal spores are inhaled from the air,” it said.
Warning symptoms include pain and redness of the eyes and nose, fever, headache, cough, shortness of breath, bloody vomiting, and an altered state of mind.
In Covid-19 patients with diabetes and immunocompromised people, mucormycosis must be suspected if there is sinusitis, unilateral facial pain or numbness, blackish discoloration over the bridge of the nose or palate, toothache, blurred or double vision with pain, skin lesions, thromboses, chest pain and worsening respiratory problems, it said.
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– ICMR (@ICMRDELHI) May 9, 2021
The main risk factors for this disease include uncontrolled diabetes mellitus, steroid immunosuppression, prolonged ICU stay, malignancy, and voriconazole therapy.
To prevent the disease, blood sugar levels should be monitored post-Covid discharge and also in diabetics; Steroids should be used with caution regarding the right time, dose, and duration. Clean, sterile water should be used in humidifiers during oxygen therapy. and antibiotics and antifungal drugs should be used correctly, it said.
The disease can be treated by controlling diabetes, stopping immunomodulating drugs, reducing steroids, and performing extensive surgical debridement to remove any necrotic materials.
Medical treatment includes installing a peripherally inserted central catheter, maintaining adequate systemic hydration, intravenous infusion of normal saline before the amphotericin B infusion and antifungal therapy for at least six weeks, and clinical monitoring of the patient with radio imaging for response and the Recognizing the progression of the disease said.
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