Immortality, the fountain of youth or the idea of living forever have been one of the greatest wishes for centuries, as Mark Twain famously said: “Life would be infinitely happier if we were only born at the age of 80 and could gradually approach 18. ” Now a group of researchers from Singapore is investigating what the longest life of a human system is.
The researchers at the biotech company Gero from Singapore in a Article published in the journal Nature Communication point to an underlying “aging rate” that defines the lifespan between 120 and 150 years. Entitled “Longitudinal Analysis of Blood Markers Shows Progressive Loss of Resilience and Predicts the Limit of Human Lifespan,” the paper says that death is an intrinsic biological property that is independent of stressors.
To assess this trend, the researchers looked at changes in blood cell counts and the daily number of steps people took. They examined health data from large groups from the US, UK, and Russia. “Human aging has universal characteristics that are common to complex systems that are on the verge of decay,” the researchers said in a statement.
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Experts believe research could guide drug development to slow the process and extend health margins. (Photo: Getty)
Led by Timothy V. Pyrkov, the team observed that with age, factors beyond disease caused a predictable and gradual decline in the body’s ability to return blood cells. They found that the rate of decline determines when this resilience disappears completely and leads to death.
They found that the age of complete loss of resilience ranges from 120 to 150 years.
Speaking to Scientific American, study co-author Peter Fedichev, who founded Gero, said, “Although most biologists would consider blood cell counts and step counts to be quite different, the fact that both sources draw exactly the same future suggests to point out that this aging component is real. “
The more interesting observation of the research was the fact that resilience drops sharply from the mid-30s to the mid-40s, and the body slowly loses its ability to manage and recover from stress.
The team observed that with age, the factors beyond disease led to a predictable and gradual decline. (Photo: Getty)
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“This work explains why even the most effective prevention and treatment of age-related diseases could only improve the average but not the maximum lifespan if true antiaging therapies were not developed,” added US co-author Andrei Gudkov of Roswell Park Comprehensive cancer center.
Experts believe research could guide drug development to slow the process down and extend health margins, as recovery rate is a major sign of aging.
It should be noted that the oldest person on record to have ever lived, Jeanne Calment, died in France at the age of 122.
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